ANI Monitoring Systems

The ANI (Analgesia Nociception Index) allows a direct measurement of the activity of the autonomic nervous system (ANS) through the analysis of its parasympathetic component via the respiratory sinus arrhythmia. Our index uses brief and rapid heart rate variations induced by each respiratory cycle (spontaneous or artificial) in order to quantify the parasympathetic tone.

Developed in order to provide clinicians a monitoring system of analgesia matching the requirements of routine clinical practice, in other words easy to use, easy to interpret, reliable and continuous… The ANI is a numerical value that evolves between 0 and 100. Our index quantifies the activity of parasympathetic part of the autonomic nervous system.

ANI has been originally developed to predict the occurrence of a hemodynamic response (defined as more than 20% increase of heart rate and/or blood pressure) under general anesthesia. However, our technology also proved her reliability on conscious patients before anesthesia, in intensive care units or in the recovery room. The predictive ability of the ANI has been demonstrated by several international studies that have shown that the ANI is significantly decreased within 5 minutes before the onset of hemodynamic reaction.